Breast Feeding
 

Breast Feeding

    

Breast Feeding

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Breast Feeding
 

PREGNANCY

BREAST FEEDING

 

J Pediatr Gastroenterol Nutr. 2006 May;42(5):568-572.

Breast-feeding Duration and Childhood Acute Leukemia and Lymphomas in a Sample of Turkish Children.

Altinkaynak S, Selimoglu MA, Turgut A, Kilicaslan B, Ertekin V.

*Department of Pediatrics, ?Division of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Ataturk University, Erzurum; and the ?Department of Pediatrics, Division of Pediatric Gastroenterology, Hepatology and Nutrition, Faculty of Medicine, Inonu University, Malatya, Turkey.

Objectives:

: Whether breast-feeding is associated with decreased incidence of the lymphoid malignancies in children is uncertain. We evaluated childhood acute leukemia and lymphoma in relation to duration of breast-feeding.

Methods:

: We investigated this issue in a case-control study comprising 137 patients, aged 1 to 16 years, with acute lymphocytic leukemia (ALL), acute myeloid leukemia (AML), Hodgkin or non-Hodgkin lymphoma, in addition to 146 controls matched for age and sex.

Results:

: The median duration of breast-feeding among patients was shorter than that of controls (10 vs 12 months). Patients with ALL and AML had shorter mean breast-feeding duration compared with healthy children (P = 0.001 and P < 0.001, respectively). The shortest mean breast-feeding duration was noted in the children with AML.Breast-feeding for a duration of 0 to 6 months, when compared with feeding of longer than 6 months, was associated with increased odds ratios (ORs) for ALL [OR = 2.44, 95% confidence interval (CI) = 1.17-5.10], AML (OR = 6.67, 95% CI = 1.32-33.69), Hodgkin lymphoma (OR = 3.33, 95% CI = 0.60-18.54), non-Hodgkin lymphoma (OR = 1.90, 95% CI = 0.68-5.34) and overall (OR = 2.54, 95% CI = 1.51-4.26).

Conclusions:

: Our findings suggest that breast-feeding of more than 6 months is protective against childhood lymphoid malignancies, especially for AML and ALL.

 

 

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