Ann Pharmacother. 2005 Oct;39(10):1710-3.
Treating pregnancy-related nausea and vomiting with ginger.
Raabe College of Pharmacy, Ohio Northern University, Ada, OH 45810-1078,
USA.
Objectives:
To review literature assessing the safety and efficacy of the
use of ginger to treat nausea and vomiting in pregnancy.
Data Sources:
Iowa Drug Information Service (1966-September 2004), International
Pharmaceutical Abstracts (1971-September 2004), MEDLINE (1966-September
2004), and EMBASE (1966-September 2004) were searched. Key terms
included ginger, nausea, vomiting, emesis, and pregnancy. DATA
SYNTHESIS: Studies evaluating the safety and efficacy of ginger in the
management of nausea and vomiting in pregnancy were reviewed. Various
doses and forms of ginger were used to treat women during their first
and second trimesters of pregnancy. Ginger has been shown to improve the
symptoms of nausea and vomiting compared with placebo in pregnant women.
Conclusions:
While data are insufficient to recommend ginger universally
and there are concerns with product quality due to limited regulation of
dietary supplements, ginger appears to be a fairly low-risk and
effective treatment for nausea and vomiting associated with pregnancy.
In low doses, this may be appropriate for patients not responding to
traditional first-line therapies.