Fertil Steril. 2006 Sep;86(3):742-4.

The levonorgestrel-releasing intrauterine device reduces CA-125 serum levels in patients with endometriosis.

de Sa Rosa e Silva AC,Rosa e Silva JC,Nogueira AA,Petta CA,Abrao MS,Ferriani RA.

Department of Obstetrics and Gynecology, School of Medicine of Ribeirao Preto, University of Sao Paulo, Ribeirao Preto, Brazil. anasars@convex.com.br This study compared the long-term effects of the levonorgestrel-releasing intrauterine device with those of GnRH agonist administration on serum levels of CA-125 in patients with endometriosis. The levonorgestrel-releasing intrauterine device was found to be as efficient as GnRH agonist in reducing CA-125 serum levels. 

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