The FTO gene has consistently been associated with obesity across multiple populations. However, to date it was not known whether the association between genetic variation in FTO and obesity is mediated through effects on energy intake or energy expenditure. Wardle's group have recently demonstrated (July 2008) that the commonest known FTO obesity-risk gene is likely to exert at least some of its effects by influencing appetite. Those with this obesity-risk gene do not have their appetite satiated easily so that they have a genetic tendency which tends to make them eat more.
0802
Medical Treatment
of Stress Urinary Incontinence
22nd July 2008
The efficacy of
venlafaxine started early and the clinical
efficacy associated with the use of the drug
continued in the following months. Venlafaxine
should be considered a clinically efficient
alternative drug in the treatment of stress
urinary incontinence.0801
Preventing Spina
Bifida
18th July 2008
A study from
China suggests that multivitamin supplement
containing folic acid taken from a time point of
2 months before conception and continuing until
completion of the second month after conception
and taken more than five times per week can
significantly reduce the risks of NTDs.0801
Improving sexual
satisfaction.
15th July 2008
Sildenafil may improve clitoral blood flow and
increase sexual satisfaction in postmenopausal
women with orgasmic dysfunction.0802
12th May 2008
Letrozole and
Anovulatory Infertility
known to be a coital problem, either elucidated from the history or perhaps from repeated observation of absence of sperm on post-coital testing.
The aromatase inhibitor letrozole appears to
constitute a good alternative to CC-gonadotropin
in patients with unexplained infertility
undergoing COH cycles combined with IUI therapy.0802
Mullerian inhibiting substance has been
studied extensively in the context of in-vitro
fertilization and has been correlated with
several outcome parameters.0801
- Infertility
Tobacco compounds exert
a deleterious effect on the process of ovarian
follicle maturation. This effect is expressed by
worse in-vitro fertilization parameters in
cycles performed on women with smoking habits.
Also, uterine receptiveness is significantly
altered by the smoking habit. In men, cigarette
smoking reduces sperm production. Spermatozoa
from smokers have reduced fertilizing capacity,
and embryos display lower implantation rates.
Even in-utero exposition to tobacco constituents
leads to reduced sperm count in adult life.
Couples in reproductive age should be strongly
discouraged to smoke. -
Infertility
10th May 2008
Reassurance has been provided that after
removing intrauterine devices to restore fertility,
subsequent pregnancies occur easily and
normally.0801
Preimplantation genetic diagnosis can be
beneficial for three major subgroups of patients
with
recurrent pregnancy loss:0801
9th May 2008
Over the last few weeks, 2womenshealth has undergone a major overhaul. The pregnancy and childhealth website www.obstetric-health.com has been incorporated into this website.
The navigation menu has been revamped.
