My libido (sex drive) is low. Is there any treatment?
Maturitas. 2007 Jan 20;56(1):61-8.
The effect of tibolone versus 17beta-estradiol on climacteric symptoms in women
with surgical menopause: a randomized, cross-over study.
Somunkiran A, Erel CT, Demirci F, Senturk ML.
Abant Izzet Baysal University, Duzce Medical School, Department of Obstetrics
and Gynecology, 81620 Konuralp, Duzce, Turkey. aslisomunkiran@yahoo.com
Objectives:
To compare the effectiveness of tibolone and 17beta-estradiol on
climacteric symptoms, in a randomized, single-blind, cross-over study in
surgically menopausal women.
Material and
Methods:
Forty surgically menopausal
women were divided randomly into two groups. Group A received treatment with
tibolone for 6 months, while group B received 17beta-estradiol. After 3 weeks
washout period, treatment protocols were exchanged for another 6 months. The
climacteric symptoms were assessed with Greene Climacteric Scale at baseline,
during washout and after the treatments. Statistical analysis was done with the
Wilcoxon's Sign Rank test.
Results:
Both treatments significantly improved the
scores of all subscales with respect to baseline. However, the improvement in
psychological, somatic and sexual subscales were significantly superior in the
tibolone group compared with 17beta-estradiol group. Both treatments showed
comparable improvements in the relief of vasomotor symptoms.
Conclusion:
Our
findings suggest that tibolone may improve mood, libido and somatic symptoms in
surgically menopausal women to a greater extent than estrogen therapy alone.
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