Does HRT affect life-expectancy?

Does HRT affect life-expectancy?

The balance of evidence, in my opinion, suggests that HRT increases life-expectancy. In the Leisure World Laguna Hills study, there had been 1447 deaths after 7.5 years follow-up. Mortality was reduced by 20% in those who had taken HRT at some time in their lives. For current users who had been taking HRT for more than 15 years there was a 40% reduction in overall mortality. There were less cancer-related deaths in the HRT group. In a meta-analysis (Q33.23) of the literature published in 1992, it was calculated that in general there would be a net gain of one year for a woman starting HRT at the age of fifty. For those women most at risk of coronary heart disease, HRT would provide a net gain of two years. For women at particular risk of developing breast cancer, HRT would still provide a net gain of one year.

The American Nurses Health Study has followed 121,700 female nurses from 1976. Their latest report (1997) has continued to show lower death rates at a given age in HRT users.

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