HRT: Would the strength of HRT alter the benefit to my bones?

In a randomised study, 45 postmenopausal women were given a 25mg, 50mg or 75mg oestradiol implant. There was a correlation between the strength of implant, blood levels of oestrogen and effect on bone density. Implants seem to be more effective at increasing bone density than oral oestrogen. In one investigation, ten out of twenty postmenopausal women on long-term oral (tablet) oestrogen therapy were given implants instead. Those changing onto implants increased their bone density by more than 5% whereas those maintained on oral oestrogen did not further improve their bone density.

Q 27. 1 HRT help me with the psychological difficulties that I am experiencing around?
Q 27. 2 HRT help my mental ability?
Q 27. 3 Can HRT reduce my chance of developing heart disease?
Q 27. 4 How does HRT protect against coronary heart disease?
Q 27. 5 If I am at particular risk of heart disease, can HRT still help?
Q 27. 6 Do progestogens taken in combination with oestrogen replacement therapy have an adverse effect on heart protection?
Q 27. 7 How long should HRT be taken to reduce the risk of heart disease?
Q 27. 8 Is there any evidence that HRT will protect my bones?
Q 27. 9 Would the dose (strength) of my HRT influence its ability to protect my bones?
Q 27. 10 Are there other treatments apart from HRT for osteoporosis?
Q 27. 11 Would HRT help my skin?
Q 27. 12 Can hormone replacement therapy cure all my menopausal symptoms?
Q 27. 13 How prevalent is cancer of the breast?
Q 27. 14 What factors influence the chance of breast cancer developing?
Q 27. 15 What is the relationship between HRT and breast cancer?
Q 27. 16 I have benign breast disease. Can I take HRT?
Q 27. 17 Does a history of breast cancer mean that HRT is absolutely contraindicated?
Q 27. 18 If I started HRT early (aged 30 to 45), does this influence my chance of developing breast cancer?
Q 27. 19 Does hormone replacement therapy increase the risks of cancer of the womb?
Q 27. 20 I have had endometrial cancer and now have menopausal problems. Can I take HRT?
Q 27. 21 Does HRT have a relationship to ovarian cancer?
Q 27. 22 How does HRT relate to a blood clot (DVT - deep venous thrombosis or pulmonary embolism)?
Q 27. 23 I have varicose veins. Can I take HRT?
Q 27.24 Should HRT be discontinued before I have a major operation or leg surgery?
Q 27. 25 Does HRT increase life-expectancy?
Q 27. 26 I am still seeing periods. Could HRT have any benefits for me?
Q 27. 27 I have been told that I have fibroids. Can I take HRT?
Q 27. 28 What happens if I decide not to take HRT?
Q 27. 29 Doctors seem to promote HRT but the media cause me anxiety. Who is right?
Q 27. 30 Support Groups.

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This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London.
I do hope that you find the answers to your questions in the patient information and medical advice provided. If you still have unanswered questions, please consider entering them into one of our forums and I will try to assist you.
DISCLAIMER

The aim of this web site is to provide a general guide and it is not intended as a substitute for a consultation with an appropriate specialist in respect of individual care and treatment.