Authors:
Brambilla DJ. McKinlay SM.
Institution:
New England Research Institute, Inc., Watertown, MA 02172.
Title:
A prospective study of factors affecting age at menopause (1989-631).
Source:
Journal of Clinical Epidemiology. 42(11):1031-9, 1989.
Abstract:
This paper describes a multivariate analysis of a 3-year prospective study of the covariates of age at menopause among women who were randomly sampled from a general population. This approach avoids three problems that may account for the inconsistent results of prior studies: recall bias in retrospectively collected data, failure to control confounding in data analyses, and self-selection in the target populations. At baseline, the 2014 subjects in this study were 46.5-56.5 years old and still menstruating. Median age at last menstruation estimated from a model of the marginal distribution of age at menopause, was 50.7 years. When covariates were considered singly, age at menopause varied with smoking, education and income but not with marital status, parity, location, height, weight or use of either oral contraceptives or menopausal estrogens. Multivariate analyses showed that education and income were confounded with smoking status. The results indicate that many previously identified sources of variation in age at menopause reflect confounding with smoking and self-selection in target populations, rather than real effects.
Please click on the required question.
- 1 What will happen to me at my menopause?
- 2 Why does nature put women through the menopause?
- 3 Is life-expectancy changing?
- 4 What happens to my reproductive hormones at the menopause?
- 5 What non-hormonal changes occur at the menopause?
- 6 What problems might I have as a result of my menopause?
- 7 When am I likely to reach my menopause?
- 8 What is a premature menopause?
- 9 What are hot flushes and will HRT reduce them?
- 10 What causes hot flushes and night sweats?
- 11 Can my bladder problems be related to the menopause?
- 12 Can the menopause be associated with psychological problems.
- 13 How long can my menopausal (climacteric) symptoms last?
- 14 Is there a test that will accurately determine when my menopause has occurred?
- 15 Is it normal to experience heavy periods before the menopause?
- 16 How are heavy periods around the time of the menopause treated?
- 17 Is there a need to investigate vaginal bleeding after the menopause (postmenopausal bleeding)?
- 18 What could be the cause of vaginal bleeding after the menopause?
- 19 What is atrophic vaginitis?
- 20 What local genital symptoms can be associated with the menopause?
- 21 I have gone through the menopause and now have some bleeding (postmenopausal bleeding PMB). What will my gynaecologist wish to do?
- 22 Could I have any other long-term medical problems resulting from my menopause?
- 23 What is coronary heart disease?
- 24 What is osteoporosis?
- 25 Where else can I obtain further information?
- 26 Could I have some recommended menopause support groups.
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