What is meant by intermenstrual bleeding?

Intermenstrual bleeding (IMB) is bleeding between periods that is not associated with intercourse (post-coital bleeding – PCB). Bleeding about fourteen days before periods may be related to ovulation or a little bleeding for a day or two before the period begins properly (premenstrual spotting) may be more of a nuisance than a medical anxiety.

There are a variety of causes for IMB. The bleeding may be coming from the cavity of the womb with causes including those for heavy periods (6). The bleeding could be arising from the cervix or vagina. Whereas heavy regular periods are almost invariably due to benign conditions, intermenstrual bleeding can occasionally be the first indication of more worrying disease.

Physical examination by your doctor should detect problems around the cervix or the vagina. Serious disease within the uterus is unusual before the age of forty. If you are less than forty years old, hormone treatment may resolve the problem. If the IMB persists despite medication or if you have reached forty, further investigation including hysteroscopy and endometrial curettage are usually recommended.

A forty-five year old lady had been happy with a LNG- intrauterine system (Mirena) for three years. She then developed a little irregular bleeding. On examination her uterus was a little bulky but there were no other problems. Ultrasound demonstrated a few small fibroids. Endometrial biopsy showed inflammation and progestogen effects. The bleeding settled completely with a course of antibiotics.

A thirty-eight year old lady presented with intermenstrual bleeding. She had one child but then had difficulty conceiving. She was overweight and there had been evidence of PCO (Q7.1). Hysteroscopy and D and C (hysteroscopy D and C Q 24.12) were performed. The histology of the endometrium (lining of the uterus) demonstrated severe atypia (abnormal cells) and after full discussion hysterectomy (hysterectomy) with bilateral salpingo-oophorectomy (removal of both ovaries and Fallopian tubes -23) was performed. The histology of the uterus showed foci of malignancy. As the malignancy was detected early, radiotherapy was not required and the prognosis is excellent.


Women's Health


Please click on the required question.

Women's Health

Thank you for choosing to visit us.


This is the personal website of David A Viniker MD FRCOG, retired Consultant Obstetrician and Gynaecologist - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.
I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.

I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.

intermenstrual bleeding

The aim of this web site is to provide a general guide and it is not intended as a substitute for a consultation with an appropriate specialist in respect of individual care and treatment.

David Viniker retired from active clinical practice in 2012.
In 1999, he setup this website - www.2womenshealth.com - to provide detailed
information many of his patients requested. The website attracts thousands of visitors every day from around the world.
Website optimisation (SEO) has became more than an active hobby. If you would like advice on your website, please visit his website Keyword SEO PRO or email him on david@page1-on-google.com.
David Viniker Linkedin Profile