How are vaginal infections treated?
From a theoretical point of view, one should usually await the results of investigations before commencing treatment. In clinical practice one is keen to make an early start in assisting patients and it is common practice to commence treatment on the basis of clinical observations and
Adjust
treatment subsequently according to investigation results.
Candida may respond to Nystatin (Nystan BMS) vaginal pessaries and cream. The full course of 14 days should be followed. Candida is sensitive to imidazole derivatives (Table 22.1), which are usually applied locally as creams or pessaries.
Table 22.1 Imidazoles used for the treatment of genital candida infections.
|
Imidazole Derivative |
Preparation |
Manufacturer | |
Clotrimazole |
Canesten |
Bayer | |
Clotrimazole |
Masnoderm |
Dominion | |
Econazole |
Ecostatin |
BMS | |
Econazole |
Gyno-Pevaryl |
Janssen-Cilag | |
Fenticonazole |
Lomexin |
Dominion | |
Isoconazole |
Travogyn |
Schering | |
Miconazole |
Gynodaktarin |
Janssen-Cilag |
The vaginal creams may be applied internally for vaginal infections and externally for vulval infections. The creams may also be applied to the penis of the partner particularly when there are recurrent infections. There are four pessaries designed for single application. These are Canesten-1, Ecostatin-1, Gynokatarin-1 and Gyno-Pevaryl 1.
Three preparations are taken orally fluconazole (Diflucan 150 Pfizer), ketoconazole (Nizoral- Janssen-Cilag) and itraconazole (Sporanox- Janssen-Cilag).
The vaginal creams may be applied internally for vaginal infections and externally for vulval infections. The creams may also be applied to the penis of the partner particularly when there are recurrent infections. There are four pessaries designed for single application. These are Canesten-1, Ecostatin-1, Gynokatarin-1 and Gyno-Pevaryl 1. Three preparations are taken orally fluconazole (Diflucan 150 Pfizer), ketoconazole (Nizoral- Janssen-Cilag) and itraconazole (Sporanox- Janssen-Cilag).
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