Authors:

Gornall RJ. Beynon DWG. Shepherd NJ. Boyd IE.

Institution:

R.J. Gornall, Department Obstetrics Gynaecology, Princess Anne Hospital, Coxford Road, Southampton SO16 5YA; United Kingdom.

Title:

Topical antiseptic agent after large loop excision of the transformation zone: Results of a randomised controlled trial. (1999-2898)

Source:

Journal of Obstetrics and Gynaecology. Vol 19(5) (pp09-510), 1999.

Abstract:

One hundred patients undergoing large loop excision of the transformation zone (LLETZ) were randomised to receive postoperative local treatment with sultrin (sulphathiazole 3.42%, sulphacetamide 2.86%, sulphabenzamide 3.7%) pessaries: one pessary twice daily for 5 days, or no treatment. Outcome measures included duration and severity of vaginal bleeding, discharge, pelvic pain, need for oral antibiotic therapy and unplanned hospital admission. There was no significant difference in the severity of symptoms in the treatment and control groups for bleeding, discharge or pain, averaged over the study period. Postoperative morbidity following LLETZ was frequent but mild. Use of prophylactic antiseptic agents is not recommended.


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