Gynecol Oncol. 2004 Jun;93(3):575-85.
Diagnosis and
treatment of gestational trophoblastic disease: ACOG Practice Bulletin No. 53. The American College of Obstetricians and
Gynecologists, 409 12th Street, SW, PO Box 96920, Washington, DC 20090-6920,
USA. soper001@mc.duke.edu Gestational trophoblastic disease comprises a spectrum of interrelated
conditions originating from the placenta. Other terms often used to refer to
these conditions include gestational trophoblastic neoplasia and gestational
trophoblastic tumor. Histologically distinct disease entities encompassed by
this general terminology include complete and partial hydatidiform moles,
invasive moles, gestational choriocarcinomas, and placental site trophoblastic
tumors. Before the advent of sensitive assays for human chorionic gonadotropin
(hCG) and efficacious chemotherapy, the morbidity and mortality from gestational
trophoblastic disease were substantial. At present, with sensitive quantitative
assays for beta-hCG and current approaches to chemotherapy, most women with
malignant gestational trophoblastic disease can be cured and their reproductive
function preserved. The purpose of this document is to address current evidence
regarding the diagnosis, staging, and management of gestational trophoblastic
disease.
Please click on the required question. Thank
you for choosing to visit us. This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT. I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.
