How successful is infertility treatment?

Fertil Steril. 1997 Apr;67(4):717-23.

Objectives:

To determine accumulated conception and live birth rates in ovum donation.

Design:

Retrospective study from a computer database. Pregnancies with one gestational sac observed by ultrasound have been included as conceptional cycles and pregnancies that resulted in one live child were recorded for the analysis of the live birth rates. Life table analysis was applied.

Setting:

Oocyte donation program at the Instituto Valenciano de Infertilidad.

Patients:

Three hundred ninety-seven recipients undergoing a total of 627 ETs were analyzed.

Interventions:

Ovarian stimulation and ovum pick-up in donors. Uterine ET in recipients after appropriate exogenous steroid replacement. MAIN OUTCOME MEASUREMENT(S): Accumulated and estimated (95% confidence intervals [CI]) conception and live birth rates in the oocyte donation program as well as considering age and cause of infertility of the recipients.

Results:

Pregnancy rate after one cycle was 53.4% (CI 50.9% to 55.9%), with a delivery rate of 42.6% (CI 40.1% to 45.1%). Accumulated pregnancy rate increased up to 94.8% (CI 90.6% to 99.0%) after four transfers. Similarly, live birth rates reached 88.7% (CI 88.1% to 89.3%) after four attempts of ET by ovum donation. Cycle fecundity rates were maintained at approximately 50% after each attempt. Implantation rate was 18.3% (430/2,340 replaced embryos). Age and cause of entering the program did not influence the overall results of ovum donation.

Conclusions:

Oocyte donation is a successful treatment modality for infertile couples that offers even higher success rates than natural conception. No difference in cumulative pregnancy rate was observed regardless of recipient age, indication for oocyte donation, or number of cycles attempted.

Please click on the required question.

• Q 11. 1 How successful is infertility treatment?
• Q 11. 2 How can we compare infertility treatments?
• Q 11. 3 How can we compare outcomes between different fertility units?
• Q 11. 4 Are treatments for infertility improving?
• Q 11. 5 Is there an increased chance of miscarriage following infertility treatment?
• Q 11. 6 Is there an increased chance of ectopic pregnancy following infertility treatment?
• Q 11. 7 What is a heterotopic pregnancy?
• Q 11. 8 What problems can occur with multiple pregnancy?
• Q 11. 9 What is selective termination of pregnancy?
• Q 11. 10 How can the pregnancy risks following infertility treatment be reduced?
• Q 11. 11 We have had infertility treatment which has been successful. How will our pregnancy be cared for?
• Q 11. 12 If we have infertility treatment, will our baby be healthy?
• Q 11. 13 What are the psychological effects of infertility? information?
• Q 11. 14 Where can I obtain more information?
• Q 11. 15 Support Groups.
  

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This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.

I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.

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