Hostile cervical mucus may be more acidic than normal. Treatment with sodium bicarbonate (a level teaspoonful dissolved in half a pint of lukewarm water), and 40ml of the solution introduced into the vagina with a syringe about two hours before coitus, can significantly improve pregnancy rates. Oestrogens (e.g. Premarin 0.625) have been administered in the preovulatory phase from day 9 to day 13 of the menstrual cycle for cervical mucus factor infertility. Mucus hostility may be associated with antibodies being produced against sperm. At one time, sperm antibody tests were arranged and steroids administered if the results were positive. Steroid treatment has some dangers and these days artificial insemination (Q10.23) or IVF seem more appropriate.
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