Authors:
Lewit N. Kol S. Ronen N. Itskovitz-Eldor J.
Institution:
Department of Obstetrics/Gynecology, Rambam Medical "center", P.O. Box
9602,Haifa 31092; Israel.
Title:
Does intravenous administration of human albumin prevent severe ovarian hyperstimulation syndrome? (1996-1520).
Source:
Fertility and Sterility. Vol 66(4) (pp54-656), 1996.
Abstract:
Objectives:
To report our experience with IV albumin as a means to prevent ovarian hyperstimulation syndrome (OHSS) in high-risk patients.
Design:
Retrospective case-series.
Setting:
University hospital-based IVF program.
Patients:
Five women undergoing controlled ovarian stimulation for IVF. Based on previous history and/or E2 measurements and number of ovarian follicles, these patients were considered to be at high risk for developing OHSS. Interventions: Intravenous albumin was given at the time of oocyte retrieval. Additional doses were given 12 and 24 hours later.
Main Outcome Measure:
Development of OHSS.
Results:
Four patients developed OHSS; two of them had the severe form of the syndrome.
Conclusions:
Severe OHSS may develop in high-risk patients despite the prophylactic administration of IV albumin.
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