Investigations leave us with unexplained infertility.How can this be? i-checksum="5479" ends

Fertil Steril. 2000 Feb;73(2):330-3.

Antiphospholipid antibodies and in vitro fertilization success: a meta-analysis.Hornstein MD,Davis OK,Massey JB, Paulson RJ,Collins JA.

Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. mdhornstei@bics.bwh.harvard.edu

Objectives:

To evaluate whether the presence of antiphospholipid antibodies among women undergoing IVF affects the likelihood of IVF success.

Design:

A meta-analysis of seven eligible studies on antiphospholipid antibodies and IVF outcome.

Settings, Design and Main Outcome Measures:

Odds ratios (ORs) and 95% confidence intervals (CIs) of an association between the presence of antiphospholipid antibodies and both clinical pregnancy and live birth from IVF.

Result(s):

There was no significant association between antiphospholipid abnormalities and either clinical pregnancy (OR 0.99; 95% CI 0.64-1.53) or live birth (OR 1.07; 95% CI 0.66-1.75) in IVF patients.

Conclusion(s):

The measurement of antiphospholipid antibodies is not warranted in patients undergoing IVF.

• Male Factor Infertility
• Female Tubal Factor
• Anovulation - Ovulation Induction
• Unexplained Infertility

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