Authors:
Gallardo E. Simon C. Levy M. Guanes PP. Remohi J. Pellicer A.
Institution:
Instituto Valenciano de Infertilidad, Guardia Civil 23,Valencia 46020; Spain.
Title:
Effect of age on sperm fertility potential: Oocyte donation as a model (1996-1529).
Source:
Fertility and Sterility. Vol 66(2) (pp60-264), 1996.
Abstract:
Objectives:
To determine the effect of age on sperm fecundability using oocyte donation as an in vive model.
Setting:
Oocyte donation and IVF programs at the Institute Valenciano de Infertilidad.
Patients:
Two-hundred forty couples undergoing 345 cycles of ovum donation, who were recipients of 298 donors.
Design:
Retrospective study in which four groups of oocyte donation cycles were established according to age of the male providing the semen sample: group (n = 31)<30 years; group (n = 195) 31 to 40 years; group (n = 98) 41 to 50 years; group (n = 21) >51 years, the oldest being 64 years. All donated oocytes were obtained from patients<35 years old. Main Outcome Measurements: Male age, sperm characteristics (volume, concentration, motility, morphology), fertilization, embryo quality, pregnancy, implantation, and abortion rates among recipients.
Results:
Similar sperm characteristics in fresh as well as after preparation for IVF were observed among males of different ages. Fertilization, embryo quality, pregnancy, and implantation were similar among the established groups. The mean age of the females included in each group significantly increased from group i to group.
Conclusions:
Age (up to 64 years) does not affect sperm characteristics or its ability to fertilize human eggs. Similarly, embryo development in vitro as well as implantation in recipient uteri are not affected by age of the male providing the semen sample.
Please click on the required question.
- 1 What is infertility?
- 2 How prevalent are infertility problems?
- 3 What are the main causes of infertility?
- 4 What are the objectives of our infertility investigations?
- 5 Have there been any noticeable changes in fertility requirements in recent years?
- 6 What is the effect of our age on fertility?
- 7 I smoke cigarettes. Can this have an effect on my fertility?
- 8 Does my weight influence fertility?
- 8A Obesity! How can I lose weight?
- 9 I have fibroids. Could these reduce my fertility?
- 10 I have been told that my womb has an abnormal shape and that was the way that I was born. Could this reduce my fertility?
- 11 I have endometriosis. Could this reduce my fertility?
- 12 I have been told that I have cervicitis or a cervical ectopy (erosion). Could this impair my fertility?
- 13 My doctor tells me that my womb is retroverted (tilts backwards). Could this reduce my fertility?
- 14 I have had an ectopic pregnancy. Does this affect my future fertility?
- 15 We are worried that we may have a fertility problem. What should we do?
- 16 How will our doctor be able to identify the cause of our infertility?
- 17 How can we tell if I am releasing my eggs (ovulating)?
- 18 Investigations have shown that I have a problem releasing my eggs (anovulation). What could be the cause of this?
- 19 How important are my Fallopian tubes in fertility?
- 20 How can we tell if my Fallopian tubes are functioning?
- 21a What are the causes of male factor infertility?
- 21 How can we assess male fertility?
- 22 What is the purpose of a post-coital test (PCT)?
- 23 We have had our infertility investigations and our problem remains unexplained. How can this be?
- 24 What are our chances of achieving a pregnancy?
- 25 Where can I obtain more information?
- 26 Could we have some recommended infertility support groups?
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