Absent and infrequent menstrual periods

Absent and Infrequent Periods



Absent and Infrequent Periods: Asherman's syndrome

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Amenorrhoea following endometrial curettage (hysteroscopy D and C) with no other obvious cause for amenorrhoea would suggest Asherman's syndrome. The endometrium (lining of the womb) is replaced by scar tissue the diagnosis being confirmed by hysteroscopy.

Hysteroscopy and hysteroscopic surgery have been the gold standard of diagnosis and treatment respectively for this condition. This syndrome occurs mainly as a result of trauma to the gravid uterine cavity, which leads to the formation of intrauterine and/or intracervical adhesions. Despite the advances in hysteroscopic surgery, the treatment of moderate to severe Asherman syndrome still presents a challenge. Furthermore, pregnancy after treatment remains high risk with complications including spontaneous abortion, preterm delivery, intrauterine growth restriction, placenta accrete or praevia, or even uterine rupture. 0801

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