Absent and Infrequent Periods: What is oligomenorrhoea?

Alvarez NR,Lee TM,Solorzano CC.

Dewitt Daughtry Family Department of Surgery, Division of Endocrine Surgery, University of Miami/Jackson Memorial Medical Center and Sylvester Comprehensive Cancer Center, Miami, Florida 33101, USA.

Androgen insensitivity syndrome (AIS) is an X-linked recessive disorder characterized by varying degrees of feminization secondary to androgen receptor insensitivity. We report a case of a 34-year-old female with complete androgen insensitivity who presented with a history of primary amenorrhea and two intra-abdominal gonads found on CT scan. The patient underwent successful laparoscopic bilateral gonadectomy without complications. AIS is present in 1:20,000 to 64,000 males; complete androgen insensitivity is seen in 2-5:100,000 phenotypic females and should therefore be considered in any otherwise healthy female with abnormal pubertal development and infertility. Although controversial, most endocrinologists agree that gonadectomy may be performed after puberty with minimal risk of testicular neoplasm.

Related Medical Abstracts - Click on the paper title:-

• Androgen resistance. (2006-01)
• Puberty in subjects with complete androgen insensitivity syndrome. (2006-02)
• Complete androgen insensitivity syndrome: the role of the endocrine surgeon. (2005-01)
• Clinical, hormonal, behavioral, and genetic characteristics of androgen insensitivity syndrome in a Brazilian cohort: five novel mutations in the androgen receptor gene. (2003-01)
• Molecular basis of androgen insensitivity. (2001-01)

Please click on the required question.

• 1 What is amenorrhoea?
• 2  What is oligomenorrhoea?
• 3  What are true and false amenorrhoea?
• 4  What is the difference between primary and secondary amenorrhoea?
• 5  Our daughter has not started her periods yet. When should we seek medical advice?
• 6  My periods have stopped. When should I seek medical advise?
• 7  My periods have stopped. How can the cause be determined?
• 8  Can generalised ill health result cause periods to stop?
• 9  I am a keen sportswoman. Could this stop my periods?
• 10 What is hyperprolactinaemia?
• 11 Which investigations are particularly helpful in finding the cause for the cessation of my periods?
• 12 What is karyotyping?
• 13 What is Turner Syndrome?
• 14 What is the testicular feminisation syndrome?
• 15 What is the resistant ovary syndrome?
• 16 What are autoantibodies?
• 17 What is premature ovarian failure (premature menopause)
• 18 What uterine abnormalities may cause amenorrhoea?
• 19 What is Asherman's syndrome?
• 20  What are the late effects of prolonged amenorrhoea?
• 21  How can my amenorrhoea be treated?
• 22  What are the risks and benefits of hormone replacement when used for premature menopause?
• 23 My periods are coming infrequently (oligomenorrhoea). What is likely to be the causes?
• 24  How are infrequent periods investigated?
• 25  How can oligomenorrhoea be treated?
• 26  If my periods are absent or infrequent, do I need contraception?
• 27  Where can I obtain more information?
• 28  Support Groups.
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  This is the personal website of David A Viniker MD FRCOG, Consultant Obstetrician and Gynaecologist at Whipps Cross University Hospital, London - Specialist Interests - Reproductive Medicine including Infertility, PCOS, PMS, Menopause and HRT.

  I do hope that you find the answers to your women's health questions in the patient information and medical advice provided.

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