J Pediatr. 2006 Jul;149(1):43-6.
Early growth acceleration in girls with idiopathic precocious puberty.
Papadimitriou A, Beri D, Tsialla A, Fretzayas A, Psychou F, Nicolaidou
P. First Department of Pediatrics, Penteli Children's Hospital, Palea
Penteli, Athens, Greece. lix@ath.forthnet.gr
Objectives:
To determine the growth pattern of girls with idiopathic
precocious puberty (IPP) from birth until diagnosis.
Study Design:
We
studied 47 girls with IPP and 35 control girls. In each subject, height
and weight were measured at diagnosis, whereas data on height from birth
until diagnosis were taken from the personal health book of the patient.
Height standard deviation score (HSDS) and body mass index SDS were
calculated.
Results:
Mean age (+/-SD) of the girls with IPP was 7.6
(1.1) years and of control girls was 7.5 (0.9) years. At birth, HSDS of
the patients with IPP was -0.01 (0.8); at the age of 2 years, 0.42
(1.2); at the age of 4 years, 0.64 (1.1); and at diagnosis, 1.23 (1.7)
(P < .001). HSDS of control girls was 0.02 (0.8) at birth, 0.25 (0.8) at
2 years, 0.12 (0.9) at 4 years, and 0.19 (1.1) at assessment (P > .05).
There was no statistical difference between body mass index SDS of the
patients 0.6 (1.1) versus that of control girls 0.5 (1.0).
Conclusions:
The early growth acceleration pattern may be used as an additional clue
to the diagnosis of idiopathic precocious puberty.
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